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临床试验/CTRI/2024/11/076844
CTRI/2024/11/076844尚未招募不适用

Anti-retroviral susceptibility and resistance pattern among people living with HIV

Dr Akshay S1 个研究点 分布在 1 个国家目标入组 107 人开始时间: 2024年12月2日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
107
试验地点
1
主要终点
RESISTANCE PATTERN ANALYSIS

研究概览

简要总结

HIV/ AIDS is considered to be an important public health issue in the era of resistance. We are conducting a cross-sectional study to determine antiviral drug susceptibility and drug resistance pattern in HIV positive individuals. After obtaining ethical committee clearance,  consenting 107 subjects passing inclusion and exclusion criteria will be allocated. A blood sample of 10 ml will we obtained with all biohazard practices and will be analyzed by PCR, Genotyping and other relevant tests. Finally resistance pattern to each group of drugs will be tabulated and reported. This analysis will help in detection and further selection of combination of antiretroviral drugs to be used in future. This study is of public health importance.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • All HIV positive /People living with HIV(PLHIV), aged above 18 years Treatment naïve patients or on antiretroviral therapy (ART).

排除标准

  • • PLHIV with known resistance of any particular group of drugs PLHIV with viral load is below the lower limits of detection (undetectable) PLHIV on alternative medicines PLHIV not willing to participate in the study.

结局指标

主要结局

RESISTANCE PATTERN ANALYSIS

时间窗: Baseline, Week 4, Week 8 and Week 12

次要结局

  • Subjects retracting consent(Baseline Week 4 Week 8 & Week 12)

研究者

发起方
Dr Akshay S
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Akshay S

Rajarajeswari Medical College and Hospital

研究点 (1)

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