Anti-retroviral susceptibility and resistance pattern among people living with HIV
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 107
- 试验地点
- 1
- 主要终点
- RESISTANCE PATTERN ANALYSIS
研究概览
简要总结
HIV/ AIDS is considered to be an important public health issue in the era of resistance. We are conducting a cross-sectional study to determine antiviral drug susceptibility and drug resistance pattern in HIV positive individuals. After obtaining ethical committee clearance, consenting 107 subjects passing inclusion and exclusion criteria will be allocated. A blood sample of 10 ml will we obtained with all biohazard practices and will be analyzed by PCR, Genotyping and other relevant tests. Finally resistance pattern to each group of drugs will be tabulated and reported. This analysis will help in detection and further selection of combination of antiretroviral drugs to be used in future. This study is of public health importance.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)(—)
- 性别
- All
入选标准
- •All HIV positive /People living with HIV(PLHIV), aged above 18 years Treatment naïve patients or on antiretroviral therapy (ART).
排除标准
- •• PLHIV with known resistance of any particular group of drugs PLHIV with viral load is below the lower limits of detection (undetectable) PLHIV on alternative medicines PLHIV not willing to participate in the study.
结局指标
主要结局
RESISTANCE PATTERN ANALYSIS
时间窗: Baseline, Week 4, Week 8 and Week 12
次要结局
- Subjects retracting consent(Baseline Week 4 Week 8 & Week 12)
研究者
Akshay S
Rajarajeswari Medical College and Hospital
