CTRI/2025/04/085646尚未招募4 期
Effect of fentanyl and dexmedetomidine as an adjuvant to levobupivacaine in paravertebral block for post operative analgesia in the patient undergoing modified radical mastectomy: A prospective randomised double blind study
Dr Nafis Anwar1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2025年10月5日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To compare time for first rescue analgesic request
研究概览
简要总结
We will compare the effect of fentanyl and dexmedetomidine as an adjuvant to levobupivacaine for post operative analgesia in paravertebral block in cases of modified radical mastectomy
Purpose of trial is to minimise the use of intravenous analgesic agent to prevent the incidence of post operative nausea and vomiting thus reducing the duration of hospital stay and patient morbidity
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- Female
入选标准
- •ASA grade I and II Modified radical mastectomy surgery requiring general anaesthesia Written and informed consent from patient BMI 20 to 25 kg/meter square.
排除标准
- •Patient not giving consent Hypersensitivity to either study drug Patient having spinal deformity Infection at the site of block Patient having coagulopathy pregnancy and severe cardiopulmonary disease.
结局指标
主要结局
To compare time for first rescue analgesic request
时间窗: Till 24 hrs from successful paravertebral block
次要结局
- To compare Visual analogue scale score for pain & total analgesic consumption(To compare side effects like Sedation nausea vomiting bradycardia & hypotension in the post operative period till 24 hours)
研究者
研究点 (1)
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