We are trying to see the effect of fentanyl and dexmedetomidine as an additive drug to levobupivacine in blocking the nerves in thoracic area present in paravertebral space in cases of modified breast surgery to see pain relief after operation.
- Conditions
- Medical and Surgical,
- Registration Number
- CTRI/2025/04/085646
- Lead Sponsor
- Dr Nafis Anwar
- Brief Summary
We will compare the effect of fentanyl and dexmedetomidine as an adjuvant to levobupivacaine for post operative analgesia in paravertebral block in cases of modified radical mastectomy
Purpose of trial is to minimise the use of intravenous analgesic agent to prevent the incidence of post operative nausea and vomiting thus reducing the duration of hospital stay and patient morbidity
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Female
- Target Recruitment
- 50
ASA grade I and II Modified radical mastectomy surgery requiring general anaesthesia Written and informed consent from patient BMI 20 to 25 kg/meter square.
Patient not giving consent Hypersensitivity to either study drug Patient having spinal deformity Infection at the site of block Patient having coagulopathy pregnancy and severe cardiopulmonary disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare time for first rescue analgesic request Till 24 hrs from successful paravertebral block
- Secondary Outcome Measures
Name Time Method To compare Visual analogue scale score for pain & total analgesic consumption To compare side effects like Sedation nausea vomiting bradycardia & hypotension in the post operative period till 24 hours
Trial Locations
- Locations (1)
Rajendra institute of medical sciences Ranchi Jharkhand India 834009
🇮🇳Ranchi, JHARKHAND, India
Rajendra institute of medical sciences Ranchi Jharkhand India 834009🇮🇳Ranchi, JHARKHAND, IndiaDr Nafis AnwarPrincipal investigator7870929552anwarnafis99@gmail.com