The effect of vitamin D addition on treatment response in patients with schizophrenia
Phase 2
- Conditions
- Schizophrenia.A disorder in which there is an insidious but progressive development of oddities of conduct, inability to meet the demands of society, and decline in total performance. The characteristic negative features of residual schizophrenia (e.g. blunting of affe
- Registration Number
- IRCT201210163014N6
- Lead Sponsor
- Vice chancellor for research,Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Schizophrenic patients based on DSM-IV TR criteria ;aged between 18 to 65 years; treated with atypical antipsychotic drugs except clozapine ; Vitamin D deficiency (serum vitamin D concentrations less than 30 ng/ml) .
Exclusion criteria:
Patients with Acute renal failure; hepatic failure; parathyroid disease and consumption of vitamin D; parathyroid hormone; calcium and phosphorous supplements
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in Positive and Negative Syndrome Scale total score (PANSS). Timepoint: Baseline and first,second,third month. Method of measurement: PANSS Questionnaire.
- Secondary Outcome Measures
Name Time Method Serum vitamin D concentration. Timepoint: Baseline and third month. Method of measurement: ELISA.