Effect of vitamin D treatment on the improvement of metabolic syndrome
Not Applicable
Completed
- Conditions
- Metabolic syndromeNutritional, Metabolic, EndocrineMetabolic disorder, unspecified
- Registration Number
- ISRCTN21527585
- Lead Sponsor
- Shandong University (China)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 600
Inclusion Criteria
1. Male and female participants
2. Aged 35-60 years old
3. Living in Jinan, China for more than 5 years
4. Employed in an office setting
5. Has had more than 13 years of education
Exclusion Criteria
1. Use of vitamin D and calcium supplementation within 60 days of screening
2. Current use of cigarettes (self-report)
3. Alcohol abuse (defined as >14 drinks/week for men, >7 drinks/week for women)
4. Diagnosis of overt diabetes, cardiovascular disease or other systematic disease
5. Use of medications that influence vitamin D, glucose, lipid profiles or blood pressure
6. Engaging in more than 20 minutes of strenuous physical activity or exercise that causes excessive breathing and sweating more than once per week
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Weight, height, waist circumference and blood pressure<br>2. Body mass index (BMI)<br>3. Serum 25(OH)D and insulin, measured by double antibody radioimmunoassay<br>4. Plasma glucose, triglycerides, and HDL cholesterol, measured by enzymatic colorimetric assay
- Secondary Outcome Measures
Name Time Method DL cholesterol, calculated using the Friedwald equation