The Effect of Vitamin D Supplementation on Improvement of Symptoms in Asthma Patients with Vitamin D Insufficiency and Deficiency
Phase 3
- Conditions
- Asthma.Asthma
- Registration Number
- IRCT20200825048515N10
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 132
Inclusion Criteria
Patients with mild-to-moderate asthma
Patients with vitamin D insufficiency and deficiency
Being consent to participate in the study
Exclusion Criteria
Diagnosis of chronic obstructive pulmonary disease (COPD)
Sarcoidosis
Hyperthyroidism
Kidney stones
Active tuberculosis
Vitamin D intolerance
Liver failure
Kidney failure
Suffering from lymphomas or other malignant tumors that have not healed in more than two years of treatment
Treatment with anticonvulsant drugs, vitamin D supplements
Treatment with systemic corticosteroids for more than 3 months prior to study
Breastfeeding or pregnancy
a basal serum calcium concentration of >2.65 mmol / L
Exacerbation of asthma in the three months before the study
Active or inactive smoking
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Control of asthma symptoms. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Asthma Control Test (ACT score).;FEV1 parameter. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Spirometer device.;FVCparameter. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Spirometer device.;Serum vitamin D level. Timepoint: Before the intervention and three months after the intervention. Method of measurement: Radioimmunoassay method.
- Secondary Outcome Measures
Name Time Method