Multimodality Treatment Including Curative Resection of Advanced NSCLC

• Conditions: Advanced Non-small-cell Lung Cancer
• Interventions: Other: Date collection

• Registration Number: NCT04455984
• Lead Sponsor: Medical University of Vienna

Brief Summary

This study retrospectively evaluates clinical parameters and outcome of patients with advanced stage non-small cell lung cancer treated with neoadjuvant therapy followed by curative-intent surgery at the Divison of Thoracic Surgery at the Medical University of Vienna

Detailed Description

This study will be undertaken as a retrospective cohort study at Devision of Thoracic Surgery, Medical University of Vienna. All patients with non-small-cell lung cancer, who received an induction chemo- or chemoradiotherapy followed by surgery in a curative intention at the Devision of Thoracic Surgery, Medical University, will be included. The aim of this study is to evaluate peri- and postoperative clinical parameters and short- and long-term outcomes in patients.

Study Timeline

• Study Start: 2017-05-01
• Study First Submitted: 2020-06-29
• Study First Submitted QC: 2020-06-29
• Status Verified: 2020-07
• Study First Posted: 2020-07-02
• Last Update Submitted: 2020-07-02
• Last Update Posted: 2020-07-07
• Primary Completion: 2020-08-01
• Study Completion: 2020-08-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 190

Inclusion Criteria

• Patients with advanced NSCLC and multimodality treatment including curative-intent resection

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Exclusion Criteria

• Patients with early stage NSCLC
• Patients with advanced NSCLC without multimodality treatment
• Patients without curative resection

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Neoadjuvant chemoradiotherapy	Date collection	Patients with advanced NSCLC treated with neoadjuvant platinum-based chemoradiotherapy followed by curative-intent surgery
Neoadjuvant chemotherapy	Date collection	Patients with advanced NSCLC treated with neoadjuvant platinum-based chemotherapy followed by curative-intent surgery

Primary Outcome Measures

Name	Time	Method
Overall survival	18 years	* Overall survival of stage III NSCLC in resectable patients undergoing induction treatment and curative intent surgery; * Overall survival of stage III NSCLC in resectable patients undergoing induction treatment and curative intent surgery; * Overall survival of stage III NSCLC in resectable patients undergoing induction treatment and curative intent surgery Overall survival of stage III NSCLC in resectable patients undergoing induction treatment and curative intent surgery

Trial Locations

Locations (1)

Medical University of Vienna; 🇦🇹 Vienna, Austria