Effects of Fully Immersive Virtual Reality Cognitive Training Based on Instrumental Activities of Daily Living for Older Adults With Mild Cognitive Impairment
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 52
- 主要终点
- Change scores of Lawton Instrumental Activities of Daily Living
研究概览
简要总结
This study aims to (1) develop and assess the feasibility of a fi-VRCT program based on IADL for older adults with MCI, (2) implement and evaluate the effectiveness of the fi-VRCT program based on IADL in older adults with MCI, and (3) investigate the potential mechanism of the fi-VRCT program based on IADL for older adults with MCI and refine this intervention accordingly.
详细描述
As research on cognitive training methods for older adults with mild cognitive impairment (MCI) progresses, fully immersive virtual reality cognitive training (fi-VRCT) has emerged as a promising approach. While the benefits of fi-VRCT for enhancing cognitive function have been recognized, its potential to improve instrumental activities of daily living (IADL) and promote independence remains uncertain. This study addresses these questions by developing and validating a fi-VRCT program based on IADL to enhance cognitive and IADL performance among older adults with MCI.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 90 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Aged 65 or above.
- •MoCA score between 18 and
- •Capability to follow directions and do tasks.
排除标准
- •History of dementia.
- •Previous neurodegenerative illness diagnosis.
- •Severe medical or surgical problems.
- •Major psychological disorders.
- •Inability to use VR system
结局指标
主要结局
Change scores of Lawton Instrumental Activities of Daily Living
时间窗: At baseline, at week 9, and at 3-month follow-up.
The Lawton Instrumental Activities of Daily Living is commonly employed to assess participants' ability to perform daily tasks and identify early functional decline. In semi-structured interviews, participants describe how they currently perform the eight IADLs. Each item is rated based on the levels of competence, ranging from independence in performing the activity to not being able to perform it at all. Score ranges from 8 to 31 and higher scores indicate better functional ability.
Changes scores of Montreal Cognitive Assessment (MoCA)
时间窗: At baseline, at week 9, and at 3-month follow-up.
The MoCA comprises12 items, it assesses orientation to time and place, attention, concentration, short-term memory, \\working memory, visuospatial abilities, language, and executive function. Scores on the MoCA range from 0 to 30, with a higher score indicative of better global cognition. A total score of 26 or above is considered within the normal cognitive function range, while a total score of 18 to 25 indicates mild cognitive impairment
Change scores of Wechsler Memory Scale (WMS)
时间窗: At baseline, at week 9, and at 3-month follow-up.
The Wechsler Memory Scale is a neuropsychological test designed to assess memory in adults aged 16 to 90. Family Pictures, Spatial Span, and Word List will be used to evaluate visual, auditory, immediate, delayed, and working memory. For each subtest, higher scores indicate better performance in memory performance. Based on age ranges, raw scores will be transformed into scaled scores ranging from 1 to 19.
Change scores of Amsterdam Instrumental Activities of Daily Living Questionnaire, Short Version
时间窗: At baseline, at week 9, and at 3-month follow-up.
The questionnaire is informant-reported and is typically completed by a caregiver. It comprises 30 items in seven categories: household activities, household appliances, finances, work, computer use, appliances, and leisure activities. Each item is rated based on the difficulty levels in performing it, ranging from no difficulty in performing the task to no longer being able to perform it. Score ranges from 0 to 100 and lower score indicates better functional ability.
次要结局
- Change scores of Stroop Color-Word Test(At baseline, at week 9, and at 3-month follow-up.)
- Change scores of Digit Span(At baseline, at week 9, and at 3-month follow-up.)
研究者
I-Chen Chen
Assistant Professor
Da-Yeh University