NL-OMON51711
Recruiting
Not Applicable
Stress system dynamics in childhood trauma-related depression - REACT
Amsterdam UMC0 sites120 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Depression
- Sponsor
- Amsterdam UMC
- Enrollment
- 120
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •General inclusion criteria:
- •\- Mastery of Dutch language
- •\- Age of \>\= 18 years
- •\- Willingness and ability to give written informed consent
- •\- Normal or corrected\-to\-normal vision
- •Additional inclusion criteria for the patient groups (i.e., MDD\+CT and MDD\-CT):
- •\- Moderate to severe depression
- •\- Score \>\= 26 on the Inventory of Depressive Symptoms\-Self Report
- •(IDS\-SR) (Rush et al., 2000\)
- •\- DSM\-5 diagnosis of major depression disorder (MDD), confirmed with clinical
Exclusion Criteria
- •General exclusion criteria:
- •\- Speech impairments
- •\- Other lifetime severe psychiatric comorbidity (bipolar disorder, psychotic
- •disorder) or current alcohol/drug dependence
- •\- Primary diagnosis of post\-traumatic stress disorder (PTSD) or Acute Stress
- •Disorder (ASD)
- •\- Lifetime diagnosis of borderline personality disorder (BPD)
- •\- Any acute somatic or acute endocrine disease (e.g., acute asthma)
- •\- Taking any medication known to influence endocrine systems
- •\- Chronic benzodiazepine use (and sporadic use on the days of the lab visits)
Outcomes
Primary Outcomes
Not specified
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