Evaluation of the effect of combined vitamin B12, folic acid and iron supplementation on hematological and biochemical markers in dimorphic anemia in pregnancy- A Comparative Study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 74
- 试验地点
- 1
研究概览
简要总结
This study aims to evaluate the effect of adding vitamin B12 to iron and folic acid supplementation on hematological and biochemical markers in pregnant women diagnosed with dimorphic anemia. Dimorphic anemia in pregnancy is commonly due to combined iron and vitamin deficiency. This is a prospective interventional parallel group randomized comparative study. A total of 74 pregnant women with confirmed dimorphic anemia will be enrolled and randomly divided into two groups of 37 participants each. The control group will receive iron and folic acid as per standard treatment. the intervention group will receive vitaminB12 along with iron and folic acid. Hematological parameters such as hemoglobin and red blood cell indices and biochemical parameters including serum Vitamin B12 levels will be measured at baseline and after treatment. The study will compare the improvement in these parameters between the two groups to determine the additional benefits of vitamin B12 supplementation in dimorphic anemia during pregnancy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 35.00 Year(s)（—）
- 性别
- Female
入选标准
- •Hemoglobin less than 11g per dl confirmed by laboratory investigation and peripheral smear showing dimorphic anemia.
排除标准
- •women with anemia due to chronic illnesses, history of hematological disorders (thalassemia, sickle cell anemia, aplastic anemia), women are already receiving vitaminB12 therapy, multiple pregnancies(twins/triplets), patients with thalassemia trait will be excluded from the study.
研究者
Simran Luthra
Shree Guru Gobind Singh Tricentenary University