JPRN-jRCT2011210029已完成2 期
A Clinical Trial of KRN125 to Mobilize Hematopoietic Stem Cells Into Peripheral Blood in Patients with Multiple Myeloma and Malignant Lymphoma
Shimogomi Aiko0 个研究点目标入组 64 人开始时间: 2021年8月6日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 64
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 75age old（—）
- 性别
- All
入选标准
- •Criteria for the multiple myeloma cohort
- •- Patients with histologically or pathologically diagnosed multiple myeloma
- •- Patients who achieved CR, sCR, VGPR, and PR with induction therapy
- •Criteria for the malignant lymphoma cohort
- •- Patients with histologically or pathologically diagnosed malignant lymphoma
- •- First or second CR or PR
- •Multiple myeloma cohort, malignant lymphoma cohort common criteria
- •- Patients aged 20 to 75 years or younger at the time of informed consent
排除标准
- •- Those who received allogeneic hematopoietic stem cell transplantation (Allo-SCT), autologous hematopoietic stem cell transplantation (ASCT), or CAR-T therapy
- •- Patients who have developed adverse events leading to discontinuation of hematopoietic stem-cell collection due to administration of granulocyte colony-stimulating factor (G-CSF) or apheresis
- •- Patients who have not been able to collect adequate amounts of hematopoietic stem cells with G-CSF or plerixafor administration
- •- Patients with hypersensitivity to G-CSF or plerixafor
- •- Patients with ECOG Performance status (PSs) of 2 or greater.
- •- Patients whose cardiac or pulmonary conditions were judged to be inappropriate for apheresis or ASCT.
- •- Pregnant or breastfeeding female patients
研究者
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