Effect of Various Calcium Hydroxide Combinations as Intracanal medicament for Managing Post-Operative Pain in Symptomatic Apical Periodontitis Cases: A Double Blinded Study
试验速览
- 阶段
- 2/3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- The purpose of this study is to compare and evaluate pain reduction in patients with apical periodontitis using different combinations of calcium hydroxide with saline, lidocaine and dexamethasone.
研究概览
简要总结
A total number of 45 patients reporting to the O.P.D. will be selected according to inclusion and exclusion criteria.Root canal treatment will be initiated under local anesthesia and rubber dam isolation. Working length will be established 1mm from radiographic apex and will be confirmed with peri-apical radiographs.
The apical portion of canal will be enlarged using K-files to size 3-4 files larger than the initial apical file, and the rest of the canal will be prepared using the crown down technique of canal preparation.
The patients will be randomly categorized into three groups The dentist and the patient will be blinded during allocation of patients to various groups.
GROUP A (n=15) Calcium hydroxide + Saline (0.9 % NaCl) 0.12 mg powder plus 0.14 mL liquid
GROUP B (n=15) Calcium hydroxide + 20 mg/ml Lidocaine with 0.0125 mg/ml epinephrine 0.12 g powder plus 0.14 mL liquid
GROUP C (n=15) Calcium hydroxide + Dexamethasone Phosphate 4mg/1ml 0.12 g powder plus 0.14 mL liquid
It will be placed in the canal with lentulo spiral for one week, and the tooth will be temporised with cavit.The endodontic treatment will be completed after a week.
The patient will be advised to mark at the VAS scale after every 24 hours for 7 days.
If patient complains of pain they will be prescribed a combination drug of Acelofenac (100mg), paracetamol (325mg), and Serratiopeptidase (15mg) as an escape drug
They will be asked to keep a record of analgesics taken each day. Patients will be recalled after 1 week for completion of the treatment
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Mandibular molar teeth with symptomatic apical periodontitis with either irreversible pulpitis or necrotic pulp.Patients with preoperative pain on percussion with 50 mm or above on a visual analogue scale (VAS) scale Age 18-65 years.
- •Teeth with PAI scores 1 and 2 described by Orstavik et al.
排除标准
- •Patients on preoperative analgesics and antibiotics within past month.
- •Presence of periodontal pockets more than 3 mm, sinus tract or swelling in the associated tooth Severely damaged teeth; teeth with root resorption; root fracture or ankylosis, bruxism.
- •Root canal treated tooth Immunocompromised patients, pregnant and lactating mothers Patients who are older than 65 years old.
结局指标
主要结局
The purpose of this study is to compare and evaluate pain reduction in patients with apical periodontitis using different combinations of calcium hydroxide with saline, lidocaine and dexamethasone.
时间窗: after every 24 hours for one week
次要结局
- to find any difference in pain reduction on using different vehicles with calcium hydroxide as intra canal medicaments.(at 2 months)
研究者
Dr. ANNEYSHA BHATTACHARRYA
I.T.S. DENTAL COLLEGE, GREATER NOIDA