The impact of passive heat treatment on glycaemic response during an oral glucose tolerance test in diabetic patients

Completed

Conditions: Diabetes
diabetes mellitus
10018424

Registration Number: NL-OMON51495

Lead Sponsor: niversiteit Maastricht

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 18

Inclusion Criteria

>50 years old
BMI 18.5-35 kg/m2
Diabetes mellitus type 2
Use of oral glucose lowering medication
Able to provide written informed consent

Exclusion Criteria

Insulin dependence
Changes in diabetes medication in the past 3 months
Allergy for one of the food items used
>5% weight change in the previous 6 months
Participating in a structured (progressive) exercise program, or in the past 3
months.
Frequent (once per week or more) user of infrared (or traditional) sauna in the
past 3 months
Inability to tolerate sauna/high temperatures
Smoking
Diagnosed with cardiovascular disease (e.g. unstable angina pectoris or recent
myocardial infarction), kidney failure (eGFR < 60 ml/min/1.73m2), rheumatoid
arthritis
Diagnosed musculoskeletal, GI tract, metabolic (except diabetes) or pulmonary
(e.g. COPD) disorders that are expected to influence study outcomes
Having a pacemaker, defibrillator, or any other type of metal implant

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>To assess the acute impact of PHT by means of infrared sauna bathing on<br /><br>glycaemic response as defined by the Matsuda Index in an oral glucose tolerance<br /><br>test (OGTT) in T2DM patients. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Determine plasma volume, body mass, skin and core body temperature, blood<br /><br>pressure and heart rate before and after passive heat treatment.</p><br>