Zinc and Selenium supplementation in patients with CKDu.
Phase 4
- Conditions
- Chronic kidney disease of uncertain etiology in Sri Lanka.
- Registration Number
- SLCTR/2019/001
- Lead Sponsor
- Department of Medicine, Faculty of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
• Age 18-60 years
• Able to provide informed consent and willing to complete the follow-up visit
• Estimated glomerular filtration rate between 30 and 60 ml/min/1.73m2
• Suffering from CKDu (ie other identifiable causes of CKD excluded)
Exclusion Criteria
• History of allergy to Zinc or Selenium
• Hemodialysis or peritoneal dialysis currently or within six months of recruitment
• Renal transplant recipient
• Pregnancy
• Breast feeding
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of change in eGFR and change of urine albumin/ creatinine ratio between baseline and final follow-up. eGFR will be calculated from serum creatinine using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. [At the completion of three months.]<br>
- Secondary Outcome Measures
Name Time Method Changes in body mass index, blood pressure and hemoglobin. [At the completion of three months.]<br>