Material in saliva following appliance usage.
Phase 1
- Conditions
- Health Condition 1: K00-K14- Diseases of oral cavity and salivary glandsHealth Condition 2: K089- Disorder of teeth and supporting structures, unspecified
- Registration Number
- CTRI/2022/07/044125
- Lead Sponsor
- Central Research Laboratory
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Children who require myofunctional therapy will be selected for study.
Exclusion Criteria
-Children with obesity (BMI > 95th percentile for age and gender).
-Children with asthma and chronic upper respiratory disorder.
-Children with diabetes or pre-diabetes.
-Children with acute infections.
-Children with any genetic abnormality or underlying systemic disease.
-Children with cerebral palsy or neuromuscular diseases.
-Children with prior history of sleep apnea treatment with continuous positive airway pressure (CPAP) or oral appliances/orthodontic treatment.
-Children on steroids, chronic anti-inflammatory drugs or opioid pain medication.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Alterations in TNF- alpha & MDA salivary biomarkers after use of myofynctional therapyTimepoint: 9 months
- Secondary Outcome Measures
Name Time Method nilTimepoint: nil