OUTREACH study: Urine analysis and antihypertensive treatment

Not Applicable

• Conditions: Hypertension; Circulatory System; Cardiovascular disease

• Registration Number: ISRCTN15911100
• Lead Sponsor: The University of Manchester

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-12-07
• Last Update Posted: 9 January 2023
• Study Completion: 2023-09-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 240

Inclusion Criteria

1. Male or female aged 18 years or above (min age 18 years old; no maximum age)
2. Patients previously diagnosed with and pharmacologically managed for hypertension
3. Patients with antihypertensive treatment with at least two antihypertensive medications
4. Patients willing and able to give informed consent for study inclusion including all study assessments

Exclusion Criteria

Current exclusion criteria as of 07/12/2022:
1. Recent history of admission to hospital relating to their hypertension or treatment with antihypertensive medications (< 2 weeks of baseline visit, including admission to A&E)
2. Refusal for 7-day home-based blood pressure monitoring
3. Self-reported pregnancy or breastfeeding
4. Female patients planning to conceive within the next 6 months

Previous exclusion criteria from 11/03/2021 to 07/12/2022:
1. Recent history of admission to hospital relating to their hypertension or treatment with antihypertensive medications (< 2 weeks of baseline visit, including admission to A&E)
2. Refusal for 7-day home-based blood pressure monitoring
3. Self-reported pregnancy or breastfeeding
4. Female patients planning to conceive within the next 12 months

Original exclusion criteria:
1. Recent history of admission to the hospital (<2 weeks of baseline visit, including admission to A&E)
2. Recent change in the prescribed antihypertensive medications (<2 weeks of baseline visit). Changes in antihypertensive drug dose are not considered an exclusion criterion if this is the only change within 2 weeks of the baseline visit
3. Refusal for 7-day home-based blood pressure monitoring
4. Self-reported pregnancy or breastfeeding
5. Female patients planning to conceive within the next 12 months

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean clinic systolic blood pressure (SBP) is measured in clinic with the study M3 blood pressure monitor at baseline and visit 4.