Effect of lysine supplementation on physical growth in children.
Not Applicable
- Conditions
- Health Condition 1: R625- Other and unspecified lack of expected normal physiological development in childhood
- Registration Number
- CTRI/2022/11/047484
- Lead Sponsor
- Indo-French Centre for the Promotion of Advanced Research (IFCPAR/CEFIPRA)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
normal and malnourished children n equal to 25 each Consent, assent, understanding of the study by the parent or guardians. Children with good general health and without clinical signs of physical disability will be recruited from local schools with a normal height for age Z score HAZ for the normal group and for stunted group, HAZ 2SD will be selected
Exclusion Criteria
Allergies, intolerances, hypersensitivity, severe anemia (Hb <8dL), medication use, history of infectious diseases, physical or psychiatric, or surgical intervention.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the urinary metabolites as biomarkers for amino acid sufficiency in a short-term amino acid (lysine) supplementation in undernourished compared to healthy Indian Children.Timepoint: Baseline and at each 4 weeks during the 3 months
- Secondary Outcome Measures
Name Time Method To develop the urinary metabolomic profiles for insufficiency and sufficiency states in undernourished Indian children, and to validate blood and urine metabolome during growth faltering.Timepoint: Baseline and at each 4 weeks during the 3 months