Towards the assessment of metabolic biomarkers and creatine uptake and turnover in skeletal muscles of patients with Facioscapulohumeral muscular dystrophy using MR spectroscopy
Phase 2
- Conditions
- muscle diseasemuscular dystrophy10028302
- Registration Number
- NL-OMON30391
- Lead Sponsor
- niversitair Medisch Centrum Sint Radboud
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 35
Inclusion Criteria
FSHD patients: clinically affected patients with a genetically confirmed diagnosis, moderate severity of the disease, informed consent.
Heatlhy volunteers: informed consent
Exclusion Criteria
All subjects: kidney or liverproblems (present or past), diabetes, wheelchair bound. MR contra-indication: pacemaker, cerebral clips, metal splinters, neuro stimulator, cardiac arythmias, epilepsy, severe claustrofobia, pregnancy.
Healthy volunteers: skeletal muscle problems or disease
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method