The study on metabolic and inflammatory biomarkers and gut microbiota in overweight Thai adults
- Conditions
- to investigate and compare the metabolic, inflammatory biomarkers and gut microbiota composition of normal and overweight in a nationally representative sample of Thai adults. Then, associations between will be analysed gut microbial concentrations, clinical-biochemical blood parameters and dietary patterns will be assessed.Overweight, metabolic biomarkers, inflammatory biomarkers, gut microbiota, dietary pattern
- Registration Number
- TCTR20220204007
- Lead Sponsor
- Fundamental fund Kasetsart University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Overweight (BMI more than or equal to 23 kg/m2)
Normal weight ((BMI 18.5 to 22.9 kg/m2)
20 years to 50 years of age
Exclusion Criteria
Any chronic disease
Medication for dyslipidemia, type 2 diabetes or elevated blood pressure
History of intestinal surgery
Pregnancy/breastfeeding
The use of antibiotics, pro-prebiotics within 3 months
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The comparison of metabolic biomarkers, inflammatory biomarkers and the gut microbiota composition 2 weeks after the first vist The gut microbiota will be analyzed by 16s amplicon sequencing technique, and metabolic parameters will be analyzed by blood chemistry analyzers
- Secondary Outcome Measures
Name Time Method The relationship between metabolic parameters and the gut microbiota composition and dietary pattern within one year after end of the intervention A multivariate linear regression analysis was performed in order to test associations between the gut microbiota composition and metabolic variables and diet pattern of participants