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Clinical Trials/NCT02105064
NCT02105064
Completed
Not Applicable

Repetitive Transcranial Magnetic Stimulation (rTMS) as an add-on Treatment for Resistant Obsessive-compulsive Symptoms in Patients With Schizophrenia

Hospital de Clinicas de Porto Alegre1 site in 1 country12 target enrollmentJuly 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Schizophrenia
Sponsor
Hospital de Clinicas de Porto Alegre
Enrollment
12
Locations
1
Primary Endpoint
Change of Obsessive Compulsive symptoms (using Yale-Brown Obsessive Compulsive Scale - Y-BOCS)
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

This is a study to evaluate the efficacy of rTMS for relief of obsessive-compulsive symptoms in patients with schizophrenia.

Registry
clinicaltrials.gov
Start Date
July 2011
End Date
February 2016
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of Schizophrenia (DSM-IV-TR)
  • YBOCS ≥ 16

Exclusion Criteria

  • Mental Retardation
  • Substance abuse
  • Any contraindication to rTMS

Outcomes

Primary Outcomes

Change of Obsessive Compulsive symptoms (using Yale-Brown Obsessive Compulsive Scale - Y-BOCS)

Time Frame: Baseline, after 20 rTMS sessions (an expected average of 4 weeks), and 4 weeks after end of treatment

Secondary Outcomes

  • Change of Psychotic Symptoms (using Brief Psychiatric Rating Scale - BPRS)(Baseline, after 20 rTMS sessions (an expected average of 4 weeks), and 4 weeks after end of treatment)
  • Change of Brain-Derived Neurotrophic Factor (BDNF)(Baseline, after 20 rTMS sessions (an expected average of 4 weeks), and 4 weeks after end of treatment)

Study Sites (1)

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