NCT02105064
Completed
Not Applicable
Repetitive Transcranial Magnetic Stimulation (rTMS) as an add-on Treatment for Resistant Obsessive-compulsive Symptoms in Patients With Schizophrenia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Schizophrenia
- Sponsor
- Hospital de Clinicas de Porto Alegre
- Enrollment
- 12
- Locations
- 1
- Primary Endpoint
- Change of Obsessive Compulsive symptoms (using Yale-Brown Obsessive Compulsive Scale - Y-BOCS)
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
This is a study to evaluate the efficacy of rTMS for relief of obsessive-compulsive symptoms in patients with schizophrenia.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Diagnosis of Schizophrenia (DSM-IV-TR)
- •YBOCS ≥ 16
Exclusion Criteria
- •Mental Retardation
- •Substance abuse
- •Any contraindication to rTMS
Outcomes
Primary Outcomes
Change of Obsessive Compulsive symptoms (using Yale-Brown Obsessive Compulsive Scale - Y-BOCS)
Time Frame: Baseline, after 20 rTMS sessions (an expected average of 4 weeks), and 4 weeks after end of treatment
Secondary Outcomes
- Change of Psychotic Symptoms (using Brief Psychiatric Rating Scale - BPRS)(Baseline, after 20 rTMS sessions (an expected average of 4 weeks), and 4 weeks after end of treatment)
- Change of Brain-Derived Neurotrophic Factor (BDNF)(Baseline, after 20 rTMS sessions (an expected average of 4 weeks), and 4 weeks after end of treatment)
Study Sites (1)
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