Randomized controlled trail on efficacy and safety of ARB and losartan potassium/Hydrochlorothiazide in hypertension patients

Phase 4

• Conditions: Hypertension

• Registration Number: JPRN-UMIN000009266
• Lead Sponsor: Executive office of ABC study

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2011-03-10
• Study Start: 2012-11-10
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Not provided

Exclusion Criteria

Exclusion criteria 1) Patients with IDDM 2) Patients with nephropathy (urinary albumin-to-creatinine ratio > 300mg/gCr) 3) Patients with poor controlled diabetes mellitus (HbA1c > 10.0%) 4) Patients during insulin treatment 5) Patients with poor controlled hypertension (SBP > 180 mmHg or DBP > 110 mmHg) 6) Patients with malignant hypertension 7) Patients with a critical liver damage (ALT or AST is over 3 times of normal) 8) Patients with attack of gout in past 9) Patient has had any severe cardiovascular events with hospitalization within the 6 months prior to informed consent. 10) Patient is pregnant or breast feeding, or is a female expecting to conceive within the projected duration of the study. 11) Patients with the secondary hypertension 12) Patients with non-diabetic nephropathy such as chronic glomerulonephritis, polycystic nephropathy and reniculus etc. 13) Patients with heart failure (above NYHA grade III) 14) Patient has poor controlled arrhythmia 15) Patients has treated with diuretic 16) Patients has allergia of test drugs 17) Patients who are considered to be not eligible to the study by the investigator due to medical reasons.

Study & Design

• Study Type: Interventional
• Study Design: Not specified