Immune Fitness Prediction

Completed

• Conditions: Healthy Adults

• Registration Number: NCT05078346
• Lead Sponsor: Société des Produits Nestlé (SPN)

Brief Summary

The overall objective of the study is to determine whether self-rated, perceived immune fitness (using questionnaire) is associated with biological assessment of immune fitness (immune signatures in the blood).

Detailed Description

Not available

Study Timeline

• Study Start: 2021-06-02
• Study First Submitted: 2021-08-26
• Study First Submitted QC: 2021-09-30
• Study First Posted: 2021-10-14
• Primary Completion: 2022-01-28
• Status Verified: 2022-02
• Study Completion: 2022-02-03
• Last Update Submitted: 2022-02-03
• Last Update Posted: 2022-02-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

1. Ability to understand and sign the informed consent
2. Healthy adult men and/or women, 35-65 years old
3. BMI >18 and <30 kg/m2

Exclusion Criteria

1. Volunteer who cannot be expected to comply with the protocol
2. Individuals with self-reported chronic disease; or who have any clinical condition which the investigator deems relevant for exclusion from the study,
3. Individuals with an impaired immune system that may confound immune response testing; i.e. any condition that impairs participant immune response through either the condition itself or through the treatment of the condition,
4. Family or hierarchical relationships with Clinical Innovation Lab at Nestlé Research, Lausanne, Switzerland

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Relative quantification of immune protein in plasma	6 - 12 months after the start of the trial	Proteomic analysis in plasma by proximity extension assay
Amount of cytokines expressed by peripheral blood mononuclear cells	6 - 12 months after the start of the trial	Cytokine quantification by proximity extension assay
Amount of analytes in serum	6 - 12 months after the start of the trial	Blood chemistry
Percentage of different immune cell types in whole blood	6 - 12 months after the start of the trial	Immune cell type profiling in whole blood by mass cytometry

Trial Locations

Locations (1)

Nestlé Clinical Research Unit; 🇨🇭 Lausanne, Vaud, Switzerland