Quantitative sensory testing (QST) protocol.
Completed
- Conditions
- chronische pijn (bij patienten)chronic painskin sensitivity
- Registration Number
- NL-OMON34703
- Lead Sponsor
- PRA International EDS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 400
Inclusion Criteria
Patients with chronic pain
Gender: male and female
Age: between 18 and 80 years of age, inclusive
Pathology: chronic pain history of 3 months or longer
pain has been considered by a physician to be either of neuropathic origin, or resulting from nerve damage due to diabetes mellitus, of postherpetic neuralgia, of phantom pain (i.e., pain resulting from an amputed limb)
Weight: no specific criteria;Healthy volunteers
Gender: male and female
Age: between 18 and 80 years of age, inclusive
Weight: no specific criteria
Exclusion Criteria
Patients with chronic pain:
- mental handicap;Healthy volunteers:
- history of chronic pain
- history of neurological disorders
- history of psychiatric disorders
- regular use of pain medication
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Criteria for evaluation<br /><br>Assessments:<br /><br>Detection thresholds and pain thresholds for thermal and mechanical<br /><br>stimulation, number of paradoxical heat sensations during the thermal sensory<br /><br>limen procedure, mechanical pain sensitivity, dynamic mechanical allodynia,<br /><br>temporal pain summation, vibration detection threshold, pressure pain threshold.<br /><br><br /><br>Statistical methods:<br /><br>Z-scores will be calculated for each QST parameter.</p><br>
- Secondary Outcome Measures
Name Time Method <p>n.a.</p><br>