Nifedipine vs Placebo for Maintenance Tocolysis of Preterm Labor.

Not Applicable

Completed

• Conditions: Obstetric Labor, Premature; Venous Thrombosis
• Interventions: Drug: Nifedipine

• Registration Number: NCT00185952
• Lead Sponsor: Stanford University

Brief Summary

Comparing nifedipine to placebo for the maintenance tocolysis of preterm labor

Detailed Description

To estimate whether maintenance nifedipine tocolysis after arrested preterm labor prolongs pregnancy and improves neonatal outcomes.

Study Timeline

• Study Start: 2001-11
• Study First Submitted: 2005-09-12
• Study First Submitted QC: 2005-09-12
• Study First Posted: 2005-09-16
• Primary Completion: 2007-01
• Study Completion: 2008-08
• Status Verified: 2011-06
• Last Update Submitted: 2011-06-10
• Last Update Posted: 2011-06-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 70

Inclusion Criteria

• arrested preterm labor

Exclusion Criteria

• ruptured membranes, fetal distress, placenta previa, placental abruption, maternal medical contraindication to tocolysis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Nifedipine	Nifedipine	Maintenance tocolysis with nifedipine.
Placebo	Nifedipine	Maintenance tocolysis with placebo tablets.

Primary Outcome Measures

Name	Time	Method
Achieving 37 weeks gestation	delivery

Secondary Outcome Measures

Name	Time	Method
Incidence of recurrent preterm labor	Delivery
Neonatal outcomes	Discharge of neonate

Trial Locations

Locations (1)

Stanford University School of Medicine; 🇺🇸 Stanford, California, United States