The use of remifentanil for attenuation of maternal pressor response to endotracheal intubation and surgical incision during the induction-delivery period of caesarean section performed under general anesthesia: comparison of two dosing regimens
Phase 4
- Conditions
- Stress response to anesthesia and surgery during elective caesarean section
- Registration Number
- DRKS00013556
- Lead Sponsor
- Clinic of Gynaecology and Obstetrics Clinic of Anaesthesiology University Clinical Center Nis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
Patients ASA I and II status, scheduled for elective caesarean section in general anesthesia who have given written informed consent
All patients refuse or have absolute/relative medical contraindications to regional anesthesia.
Exclusion Criteria
Exclusion criteria are: known cardiac, respiratory, neurologic, renal, endocrine, psychiatric disorders, history of drug or alcohol abuse, morbid obesity, preeclampsia, predicted difficult airway management, active labor, known fetal congenital abnormalities or signs of fetal compromise.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Our main goal is to compare the changes of maternal blood pressure, heart rate values measured after endotracheal intubation, skin incision, peritoneal incision and delivery during caesarean cestion between groups. We also compare neonatal outcome between groups (Apgar scores at 1st and 5th minute, HR, oxygen saturation, the need for resuscitative measures and umbilical venous and arterial blood gas values).
- Secondary Outcome Measures
Name Time Method