NCT04135482已完成不适用
Evaluating the Immune Status of Patients With Severe Crohn's Disease Using Single Cell Sequencing
First Affiliated Hospital of Zhejiang University1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2019年10月21日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- single cell analysis of the colonic tissue of patients with severe crohn's disease
研究概览
简要总结
Using single cell sequencing method to evaluate and compare the immune status of patients with severe CD.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •1, Patients with severe CD（CDAI>16,SES-CD>19） 2, Patients have no previous any drug therapy targeting CD or just received treatment of 5-ASA -
排除标准
- •1, patients have previous treatment of prednisone, immunosuppressive agents such as azathioprine and biologic agents such as infliximab 2, patients were diagnozed as mild-moderate CD 3, patients have other immune disordered diseases such as SLE, PBC, AIH, PSC, sjogren syndrome, ulcerative colitis, and so on.
结局指标
主要结局
single cell analysis of the colonic tissue of patients with severe crohn's disease
时间窗: 1 year
single cell analysis of the colonic tissue of patients with severe crohn's disease: inflammed and non-inflammed area from right colon or the terminal ileum
次要结局
未报告次要终点
研究者
研究点 (1)
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