Correlation of White Matter Fractional Anisotropy Measurements at 3T MRI with Neurocognitive Function in Childhood Cancer Survivors: a Pilot Study
- Conditions
- brain damage after childhood cancer1002765510057167
- Registration Number
- NL-OMON30064
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 36
Inclusion Criteria
- Age and sex matched control between 8-16 years selected from the classmates of the patient with an average cognitive performance
Exclusion Criteria
1. Psychological contraindications for MR Imaging are claustrophobia and / or need for sedation to perform MRI successfully..
2. Physical contraindication for MR Imaging metallic implants or metallic orthodontic material.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>White matter fraction anisotropy as measured by MR.<br /><br>Neurocognitive functioning of children including IQ as measured with<br /><br>intelligence testing and questionaires.</p><br>
- Secondary Outcome Measures
Name Time Method <p>The reason for refusal to participate will be registered in order to improve<br /><br>the design of future ongoing studies concerning brain imaging and<br /><br>neurocognitive outcome after childhood cancer. </p><br>