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Clinical Trials/NCT03129464
NCT03129464
Completed
Not Applicable

Effect of Cold Therapy Implementation on Multi-modal Postoperative Pain Management in Women Undergoing Laparoscopic Hysterectomy

Cleveland Clinic Florida1 site in 1 country56 target enrollmentFebruary 1, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pain, Postoperative
Sponsor
Cleveland Clinic Florida
Enrollment
56
Locations
1
Primary Endpoint
Post-operative Pain Score
Status
Completed
Last Updated
last year

Overview

Brief Summary

This is a pilot randomized controlled trial examining post-operative pain scores and outcomes after laparoscopic hysterectomy in patients prescribed cold therapy as an adjunct to routine post-operative multi-modal analgesia, compared to those patients prescribed routine multi-modal analgesia without cold therapy. All patients scheduled for total laparoscopic hysterectomy (without robotic-assistance) will be screened for eligibility in the study. If eligible, patients will be invited to participate in the study and standardized informed consent process will ensue. After surgery is completed participants will be randomized to either the control group or the study group. The study group will be prescribed the use of cold therapy to their abdominal incisions through reusable cold gel packs. The cold therapy is to be applied to participants' incisions for the first three postoperative days, in addition to routine post-operative analgesia regimen. Investigators will then collect information on pain scores, narcotic use, quality of life and surgical recovery scores.

This study aims to examine if there is a difference in post-operative pain scores with the application of cold therapy to laparoscopic abdominal incisions following laparoscopic hysterectomy, when compared to no cold therapy. Secondarily, investigators will examine post-operative quality of life scores, postoperative surgical recovery scores, as well as narcotic use among the two groups. Investigators also aim to ascertain additional information regarding total quantity of narcotics used post-operatively to aid in prescribing patterns.

Registry
clinicaltrials.gov
Start Date
February 1, 2017
End Date
July 1, 2018
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Pamela Frazzini Padilla

Clinical Fellow

Cleveland Clinic Florida

Eligibility Criteria

Inclusion Criteria

  • Patients can understand and voluntarily sign an informed consent form
  • Female gender ages 18-65
  • Scheduled for laparoscopic hysterectomy for benign indications, total or subtotal, without or without oophorectomy (standard of care involves bilateral salpingectomy)

Exclusion Criteria

  • Conversion to laparotomy
  • Diagnosis of chronic pelvic pain
  • No access to freezer at home to keep reusable cold packs cold between uses
  • Contraindications to exposure to cold therapy (history of cold allergy, cold intolerance, Raynaud's disease, cold urticaria, cryoglobulinemia, or pyoderma gangrenosum)
  • Medical contraindication to NSAID use

Outcomes

Primary Outcomes

Post-operative Pain Score

Time Frame: 24 hours post-operatively following total laparoscopic hysterectomy

Post-operative pain score on an 11 point numeric rating scale, minimum value of 0 and maximum value of 10, zero meaning no pain and 10 meaning the worst pain imaginable.

Secondary Outcomes

  • Post-operative Pain Score(72 hours post-operatively following total laparoscopic hysterectomy)
  • Patient Reported Quantity of Narcotics Used Post-operatively(72 hours post-operatively following total laparoscopic hysterectomy)
  • Quality of Life Score as Measured by the Validated Abdominal Surgery Impact Scale(72 hours post-operatively following total laparoscopic hysterectomy)
  • Surgical Recovery Score as Measured by the Validated Surgical Recovery Scale(10-14 days post-operatively following total laparoscopic hysterectomy)

Study Sites (1)

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