Acute coagulopathy and inflammation of trauma-3 - ACIT trial

Academisch Medisch Centrum0 个研究点目标入组 500 人开始时间: 待定最近更新: 2024年2月28日

适应症

试验速览

暂无简介。

•Age > 18 years
•Sustained a blunt or penetrating trauma, with at least one of the following clinical parameters:
•o Reparatory rate <10 or >25 times per minute
•o Heart rate *120 per minute
•o Systolic blood pressure < 90 mmHg
•o Oxygen saturation <90%
•o Estimated blood loss *500 mL
•o GCS * 13 or abnormal pupil size and/or reaction
•* Or clinical signs of at least one of the following diagnoses:
•o 1 femur fracture
•o Signs of flail thorax/pneumothorax/hematothorax or multiple rib fractures
•o Signs of significant abdominal injury
•o Pelvic fracture
•o Spine injury

•Patients transferred from other hospitals
•Patients presenting more than 120 minutes after time of injury
•Patients who have received more than 2000 mL of intravenous fluids prior to emergency department arrival
•Patients with burns >5% of their body surface area
•Patients taking anticoagulant medication other than aspirin (<650mg/day)
•Patients with a known bleeding diathesis
•Patients with moderate to severe liver disease (Child's classification B or C)

发起方