A CLINICAL EVALUATION OF SHATAVARYADI CHURNA IN THE MANAGEMENT OF MUTRASHMARI WITH SPECIAL REFERENCE TO UROLITHIAISIS.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Before and after treatment check for
研究概览
简要总结
Mutrashmari which is one of the ashta mahagada is the most common disorders of mutravaha srotas. Though Ayurveda is effectively being used to manage it, it is the need of hour to develop a few evidence based formulations.
Here six drugs are mixed together in equal quantity and 6 grams twice daily after food is given with tamarind juice for 21 days. The trial medicine contains the following drugs namely Shatavari, Gokshura, Kulattha, Punarnava, Varuna and Ushira. These drug are having Vedana
Shamaka, Mutrala and Ashmari Bhedana actions. Hence the clinical study was undertaken to evaluate the effect of Shatavaryadi Churna over the subjective and
objective parameters of Mutrashmari.
OBJECTIVE : The main objective of the study is to evaluate the efficacy of Shatavaryadi Churna in the management of Mutrashamari with special reference to Urolithiasis.
METHODOLOGY: Inerventional clinical study.
Drug dosage: All the six drugs in Churna form will be mixed together and 6 grams
twice daily after food for 21 days.
Anupana : Amlika swarasa (Tamarind juice)
Duration: Total duration of study was 28 days.
Follow up:
First follow up – 7th day
Second follow up – 14th day
Third follow up – 21st day
After treatment follow up – 28th day
RESULT :
Shatavaryadi Churna shown significant reduction in pain abdomen, radiating pain, burning micturition, obstruction to the flow of urine, expulsion of calculi,
reduction in number of calculi and reduction in size of calculi after the treatment.
CONCLUSION :
• The drug Shatavaryadi Churna shown significant improvement in both subjective and objective parameters.
• Marked relief was obtained in pain abdomen, radiating pain, burning micturition and obstruction to the flow of micturition.
• In current study, reduction in size and number of calculi had shown significant difference.
• The drug has shown overall relief in symptoms of the Mutrashmari.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Size of Ashmari less than 10 mm.
- •Age group between 18-70 years irrespective of gender, occupation, race and socio economic status.
- •Ureteric calculi, vesical calculi and renal calculi are included.
- •Multiple calculi less than or equal to 3 Those patients who are ready to undergo treatment as per protocol & who are ready to sign the informed consent form.
排除标准
- •Patients who are known case of severe systemic disorders like renal failure, tuberculosis, polycstic kidney and neoplasms.
- •Pregnant and lactating women.
- •Type I and Type II diabetes mellitus HIV, HBsAg Subjects with gouty arthritis.
结局指标
主要结局
Before and after treatment check for
时间窗: 21 days
Mehato Vedana in Nabhi Pradesha, Basti Pradesha, Seevani Pradesha, Mehana Pradesha (Pain while micturition)
时间窗: 21 days
Mutradaha (Burning micturition)
时间窗: 21 days
Sarudhira Mutrata (Haematuria)
时间窗: 21 days
Mutradhara Sanga (Obstructionto the flow of micturition/ frequency)
时间窗: 21 days
次要结局
- Before and after treatment check for(Mehato Vedana in Nabhi Pradesha, Basti Pradesha, Seevani Pradesha, Mehana Pradesha (Pain while micturition))