Comparing the effectiveness of two cell products and triamcinolone drug in the treatment of lichen planopillaris
Phase 1
Recruiting
- Conditions
- ichen Planopilaris.Cicatricial alopecia [scarring hair loss]
- Registration Number
- IRCT20200127046282N29
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Age between 18-60 years
Lichen planopilaris disease has been proven
Exclusion Criteria
breastfeeding
pregnancy
Infectious diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response to treatment. Timepoint: 0 and 6 months after the start of the study. Method of measurement: Lichen plano pilaris activity index.;The amount of hair loss. Timepoint: Before starting treatment and one month after the end of the treatment period. Method of measurement: Trichoscan.
- Secondary Outcome Measures
Name Time Method The level of satisfaction with treatment qualitatively. Timepoint: 2 and 6 months after the start of treatment. Method of measurement: In the qualitative questionnaire (excellent effect, good, medium, low, ineffective).;Side effects. Timepoint: Before starting treatment and one month after the end of the treatment period. Method of measurement: Questionnaire and visit.;Effectiveness. Timepoint: Before starting treatment and one month after the end of the treatment period. Method of measurement: Questionnaire and visit.
Related Research Topics
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What molecular mechanisms underlie Wharton's jelly MSC-derived conditioned medium and extracellular vesicles in treating lichen planopillaris?
How does IRCT20200127046282N29 compare MSC-derived therapies with triamcinolone for cicatricial alopecia in phase 1 trials?
Which biomarkers correlate with response to MSC extracellular vesicles versus corticosteroids in lichen planopillaris patients?
What adverse events are associated with Wharton's jelly MSC-derived products in phase 1 trials for scarring hair loss?
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