Autologous Blood for Full-thickness Macular Hole
- Conditions
- Ophthalmopathy
- Interventions
- Other: Pars-plana vitrectomy
- Registration Number
- NCT05494229
- Lead Sponsor
- Omer Othman Abdullah
- Brief Summary
Autologous blood for primary and recurrent holes
- Detailed Description
Utilizing whole autologous blood for closing both primary and recurrent holes. Here, we apply a drop of the taken whole blood over the hole, and the access blood will be aspirated on the macula with a silicon-tipped active back-flash cannula, to abolish all the possibilities of the fibrinogenic behavior of the whole blood composition, which might cause traction and recurrent hole formation. Therefore, only the hole will be filled with blood. The blood will be taken under completely sterile and aseptic conditions.
The air infusion will be raised after the valve of one of the trocars will be removed, to allow the air current to dry the clot inside the hole rapidly. Then air gas exchange will be performed to allow the clot to remain away from intraocular fluids for one to two weeks and abolish the possibility of the clot being dissolved.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 5
- Primary and recurrent holes
- Lamellar and pseudoholes
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Utilizing autologous whole blood for the full thickness macular hole Pars-plana vitrectomy It is an interventional study by performing pars-plana vitrectomy
- Primary Outcome Measures
Name Time Method Anatomical outcome The fourth week post-operatively OCT
- Secondary Outcome Measures
Name Time Method Functional outcome The fourth week post-operatively. Best corrected visual acuity
Trial Locations
- Locations (1)
Omer Othman Abdullah
🇮🇶Erbil, Iraq