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Clinical Trials/NCT02542072
NCT02542072
Completed
Not Applicable

Multi-Center Clinical Evaluation of Two Reusable Soft Contact Lenses

Coopervision, Inc.5 sites in 2 countries90 target enrollmentAugust 2015
ConditionsMyopia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Myopia
Sponsor
Coopervision, Inc.
Enrollment
90
Locations
5
Primary Endpoint
Comfort
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

The purpose of this study is to compare the subjective performance of comfilcon A lens against samfilcon A lens after 4 weeks of reusable lens wear.

Detailed Description

This will be a 90 subject, randomized, bilateral, subject-masked, dispensing, cross-over study comparing comfilcon A versus samfilcon A lenses over 8 weeks of daily wear (2 x 4-weeks). Both eyes will wear the same lens (test or control) for 4 weeks in a randomized fashion. Subjects will be masked to lens type and investigators will be masked to the lens codes.

Registry
clinicaltrials.gov
Start Date
August 2015
End Date
March 2016
Last Updated
8 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Comfort

Time Frame: Baseline, 2 weeks, 4 weeks

Subjective ratings of comfort (comfort after insertion, typical comfort just prior to removal, and overall comfort) for comfilcon A and samfilcon A assessed at baseline, 2 weeks, and 4 weeks. Scale of 0-10 (0=painful, 10=can't feel the lenses).

Secondary Outcomes

  • Wearing Times(Baseline, 2 weeks, 4 weeks)
  • Biomicroscopy Scores(Baseline, 2 weeks, 4 weeks)
  • Deterioration in Comfort(Baseline, 2 weeks, 4 weeks)
  • Overall Lens Handling(Baseline, 2 weeks, 4 weeks)
  • Film Deposits(2 weeks and 4 weeks)
  • Comfortable Wearing Time Via SMS (Short Message Service)(Days 3, 12, 26)
  • Vision Quality(Baseline, 2 weeks, 4 weeks)
  • Visual Acuity (VA)(Baseline, 2 weeks, 4 weeks)
  • Lens Centration(Baseline, 2 weeks, 4 weeks)
  • Corneal Coverage(Baseline Visit, 2 weeks follow-up, 4-weeks follow-up)
  • Post-Blink Movement(Baseline, 2 weeks, 4 weeks)
  • Lens Tightness Push-up(Baseline, 2 weeks, 4 weeks)
  • Dryness(Baseline, 2 weeks, 4 weeks)
  • Lens Surface Wetting(Baseline, 2 weeks, 4 weeks)
  • White Spot Deposits(2 weeks and 4 weeks)
  • Primary Gaze Lag(Baseline, 2 weeks, and 4 weeks)
  • Overall Fit Acceptance(Baseline, 2 weeks, 4 weeks)

Study Sites (5)

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