NL-OMON36192CompletedPhase 4
Oral Versus Intravenous Dexamethasone in Community-acquired pneumonia study - OVID study
Conditions
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Sint Antonius Ziekenhuis
- Enrollment
- 30
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •- Aged 18 years and older
- •- Presenting to the emergency room with suspected pneumonia (to be confirmed within 24 hours from admission)
- •- Pneumonia is defined as a new or progressive infiltrate on a chest X-ray plus at least two of the following criteria: cough, sputum production, temperature >38°C or <35°C, ausculatory findings consistent with pneumonia, leucocytosis or leucopenia (>10 g/l, <4 g/l or >10% rods in leucocyte differentiation), C-reactive protein >3 times the upper normal limit
- •- Corticosteroid naive at time of presentation
Exclusion Criteria
- •- Patients needing corticosteroid treatment above study medication
- •- Failure to obtain written consent to participate
- •- Patients using fenytoine, barbiturates, rifampicine, erythromycin, clarithromycine, aprepitant, colchicine, everolimus, itraconazol, ketoconazole, pazopamib, tipranavir, vinorelbin
- •- Moribund patients (defined as expected to die within 24 hours)
- •- Patients with proven or suspected allergy to dexamethasone
- •- Patient not capable of taking tablets orally
Investigators
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Not Applicable
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