Oral Versus Intravenous Dexamethasone study - OVID study

Sint Antonius Ziekenhuis0 个研究点开始时间: 2011年7月4日最近更新: 2012年12月17日

适应症

试验速览

暂无简介。

•- Aged 18 years and older
•- Presenting to the emergency room with suspected pneumonia (to be confirmed within 24 hours from admission)
•- Pneumonia is defined as a new or progressive infiltrate on a chest X-ray plus at least two of the following criteria: cough, sputum production, temperature >38°C or <35°C, ausculatory findings consistent with pneumonia, leucocytosis or leucopenia (>10 g/l, <4 g/l or >10% rods in leucocyte differentiation), C-reactive protein >3 times the upper normal limit
•- Corticosteroid naive at time of presentation
•Are the trial subjects under 18? no
•Number of subjects for this age range: 0
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 20
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 10

•- Patients needing corticosteroid treatment above study medication
•- Failure to obtain written consent to participate
•- Patients using fenytoine, barbiturates, rifampicine, erythromycin, clarithromycine, aprepitant, colchicine, everolimus, itraconazol, ketoconazole, pazopamib, tipranavir, vinorelbin
•- Moribund patients (defined as expected to die within 24 hours)
•- Patients with proven or suspected allergy to dexamethasone

发起方