Long Term Results of Combined Transpupillary Thermotherapy (TTT) Indocyanine Green (ICG) Based Photodynamic Therapy (PDT) in Choroidal Melanoma

Completed

• Conditions: Choroidal Melanoma

• Registration Number: NCT01253759
• Lead Sponsor: New England Retina Associates

Brief Summary

This is a report of 10 years results of combined Transpupillary thermotherapy (TTT) treatment with Indocyanine green (ICG) in controlling small and medium-sized choroidal melanomas.

Detailed Description

The study was done in a Clinical practice setting. Forty six eyes of 46 patients with small or medium-sized choroidal melanomas were treated with i-TTT using infrared light delivered from a diode laser. All patients were evaluated to rule out systemic metastasis and underwent a complete ophthalmological evaluation including: Slit lamp biomicroscopy, dilated fundus examination, Fluorescein angiography, Optical coherence tomography and A/B ultrasonography. Main outcome measures were: Changes in visual acuity, complications associated with the treatment and local control of the tumor.

Study Timeline

• Study Start: 2009-01
• Primary Completion: 2009-01
• Study Completion: 2009-03
• Study First Submitted: 2009-03-25
• Study First Submitted QC: 2010-12-02
• Study First Posted: 2010-12-03
• Status Verified: 2013-05
• Last Update Submitted: 2013-05-01
• Last Update Posted: 2013-05-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

• Small and medium-sized choroidal melanoma
• Patients older than 18 years old.
• Patients who can read and signed the informed consent.

Exclusion Criteria

• Patients with ocular inflammation.
• Patients with another active ocular disease.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

New England Retina Associates; 🇺🇸 Hamden, Connecticut, United States