Effects of carnosine supplementation on autism disorder
Phase 2
- Conditions
- Autism disorder.Childhood autism
- Registration Number
- IRCT2016061711689N5
- Lead Sponsor
- Deputy of research and technology of Tabriz university of medical science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
diagnosis of Autism by psychologist; age between 4-16 years old; tend to cooperation; unchanged method of medical treatment since two months before intervention and through out follow up time; not receiving other supplements; mental retardation. Exclusion criteria: any type of Chelator drugs consumption in study duration; following special diets; neurological diseases like epilepsy, Cerebral Palsy and...; all types of metabolic disorders; medical treatment method alteration during study period; disinclination to start or to continue cooperation; acceptance rate less than 75 percent.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sleep disorders. Timepoint: Beginning and eighth week of the study. Method of measurement: CSHQ questionnaire.;Gastrointestinal disorders. Timepoint: Beginning and eighth week of the study. Method of measurement: ROME3 questionnaire.;Plasma levels of Melatonin. Timepoint: Beginning and eighth week of the study. Method of measurement: ELISA.;Plasma levels of Oxytocin. Timepoint: Beginning and eighth week of the study. Method of measurement: ELISA.;Autism disorder severity. Timepoint: Beginning and eighth week of the study. Method of measurement: GARS questionnaire.
- Secondary Outcome Measures
Name Time Method Height. Timepoint: Beginning and eighth week of the study. Method of measurement: Seca stadiometer.;Weight. Timepoint: Beginning and eighth week of the study. Method of measurement: Seca scale.;Body Mass Index. Timepoint: Beginning and eighth week of the study. Method of measurement: (weight/(Height)2).;Hyperactivity. Timepoint: Beginning and eighth week of the study. Method of measurement: Conners questionnaire.