The symptoms, virology and immunity of COVID in healthcare workers
Not Applicable
Completed
- Conditions
- COVID-19 (SARS-CoV-2 infection)Infections and Infestations
- Registration Number
- ISRCTN44324934
- Lead Sponsor
- niversity of Bristol
- Brief Summary
2022 Results article in https://doi.org/10.3389/fimmu.2022.968317 (added 28/06/2024)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 79
Inclusion Criteria
Any patient-facing clinical staff member working regularly in the Children’s Emergency Department (CED) of Bristol Royal Hospital for Children, including doctors, nurses and healthcare assistants
Exclusion Criteria
1. Staff who, on average, work less than two shifts per week
2. Staff who anticipate that they will not able to complete at least 6 weeks of the study, excluding annual leave e.g. about to go on maternity leave
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method COVID-19 symptoms measured using online daily symptom diary every day for 3 months
- Secondary Outcome Measures
Name Time Method 1. COVID-19 infection measured using self-sampling of upper respiratory tract (nose, throat & saliva) - twice weekly for 3 months<br>2. Serum antibody levels and peripheral antigen-specific memory T cells measured using blood sampling at weeks 0, 6, 12, 18, and 52