Prevalence and clinicopathological characteristics of programmed death-ligand 1 expression in Thai patients with gastric cancer
Completed
- Conditions
- The primary objective is to investigate the correlation between PD-L1 expression and gastric cancer staging according to American Joint Committee on Cancer (AJCC) TNM staging, eighth edition. The secondary objectives are to investigate the correlation between PD-L1 expression and other clinicopathological characteristics and overall survival.PD-L1 expression, gastric cancer, clinicopathological characters, combined positive score, overall survival
- Registration Number
- TCTR20221031001
- Lead Sponsor
- Faculty of Medicine, Chiang Mai University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 268
Inclusion Criteria
1.Tissue samples from patients who had newly diagnosed gastric cancer and underwent either biopsy or surgical treatment in the Maharaj Nakorn Chiang Mai hospital from January 1, 2018, to December 31, 2021
2.Age more than 18 years old.
3.Tissue sample was available to assess PD-L1 expression by immunohistochemistry technique.
Exclusion Criteria
1.No recorded hospital admission or follow-up data in Maharaj Nakorn Chiang Mai hospital electronic medical record.
2.Diagnosed other types of malignancy (Gastrointestinal stromal tumor, Lymphoma, Neuroendocrine tumor, or Metastatic tumor).
3.Have other active malignancies or during chemotherapy or radiation for other malignancies.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PD-L1 expression At the beginning of study combined positive score
- Secondary Outcome Measures
Name Time Method PD-L1 expression 0, 12, 24, 36, 48, 60, 72, 84 months overall survival