Prevalence of clinical characteristics of patients with a (probable) Behçet*s syndrome in the Netherlands, a follow up cohort study.

Recruiting

• Conditions: Behcet Syndrome; Behcet's disease; 10027665

• Registration Number: NL-OMON45634
• Lead Sponsor: Jan van Breemen Instituut

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 200

Inclusion Criteria

Adult patients who fullfill the international criteria of Behcet syndrome.
Those with a clinical suspicion of Behcet syndrome.

Exclusion Criteria

none (except no informed consent)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>No endpoints were defined, since it is an observational cohort study. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>We wil record occurrence of disease manifestations and treatment given.<br /><br>Disease activity and QoL will be assessed using various questionnaires.<br /><br>We will measure NETosis by levels of circulating nucleosomes and systemic<br /><br>neutrophil activation will be assessed by released neutrophil elastase complex<br /><br>with its natural inhibitor alfa1-antitrypsine (ELA complexes) and levels of<br /><br>circulating nucleosomes.<br /><br>T cel regulation will be measured by clonal expansion. </p><br>