The Role of Hydration on Exercise Performance - ODIN

Not Applicable

Completed

• Conditions: Dehydration
• Interventions: Other: iv fluid infusion

• Registration Number: NCT02980939
• Lead Sponsor: University of Arkansas, Fayetteville

Brief Summary

During exercise in the heat, there is a need to replenish fluids in order to avoid dehydration and decrease the risk for heat illness. What drives this urge to drink is the thirst mechanism. Following ingestion of fluids, there is an inhibition of thirst before there is a replenishing of fluids. However, there is little scientific evidence of where thirst is inhibited, if this thirst inhibition is augmented by exercise and how thirst itself influence exercise performance. Further, during rehydration studies, it is very difficult to successfully blind a subject to their drinking/hydration protocol. Previous studies that have blinded a subject to their drinking have used various methods such as intravenous fluid administration and/or nasogastric tubes. Therefore, the purpose of this research is to examine the mechanistic roles thirst inhibition plays while exercising in the heat while undergoing intravenous fluid administration. Specific attention will be directed to the cardiovascular and thermoregulatory function of the individuals. All blood, cardiovascular, thermoregulatory, and perceptual measures are shown in the diagram below.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-11
• Study First Submitted: 2016-11-30
• Study First Submitted QC: 2016-12-01
• Study First Posted: 2016-12-02
• Primary Completion: 2017-03-18
• Study Completion: 2017-03-18
• Status Verified: 2017-05
• Last Update Submitted: 2017-05-27
• Last Update Posted: 2017-05-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 11

Inclusion Criteria

• Cycling Racing History category 3 or higher USA cycling certification
• maximal oxygen uptake >55 ml/kg/min

Exclusion Criteria

• History of heat stroke
• Renal, cardiovascular, metabolic diseases
• Regular medication

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Dehydration - no Thirst	iv fluid infusion	-
Euhydration - no thirst	iv fluid infusion	-

Primary Outcome Measures

Name	Time	Method
5km - Cycling Time Trial	2hour	Time to completion 5 km cycling time trial in the heat

Secondary Outcome Measures

Name	Time	Method
Rectal Temperature	2hour	Body core temperature at the end of the 5 km time trial

Trial Locations

Locations (1)

University of Arkansas - HPER; 🇺🇸 Fayetteville, Arkansas, United States