The Comparison of Cognitive Function, Symptoms of Depression and Anxiety, and Quality of Life in Patients After Hip Fracture Surgery Under General or Regional Anesthesia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postoperative Cognitive Dysfunction
- Sponsor
- University of Zagreb
- Enrollment
- 140
- Primary Endpoint
- change in cognition
- Last Updated
- 5 years ago
Overview
Brief Summary
Postoperative cognitive dysfunction is a relatively common in elderly patients after hip surgery, but exact mechanism of its onset is still unclear as well as contributing factors. There is also increased incidence of depression and anxiety. Both affect the recovery after surgery, slow it down and reduce the quality of life. Patients will be divided into two groups, operated under regional anaesthesia and operated under general anaesthesia, and monitored after surgery. Patients will be tested before and after surgery to evaluate postoperative cognitive deficits, depression and anxiety scale and health-related quality of life questionnaire.
Investigators
Tea Fabijanić, MD
MD
University of Zagreb
Eligibility Criteria
Inclusion Criteria
- •Patients intended for surgical treatment of hip fractures ≥ 60 years
- •Patients who are category ASA I to ASA III will be included in research
- •Sufficient cognitive ability
- •Only those patients who have agreed to be participants in the research and have signed the consent for participation and informed consent.
Exclusion Criteria
- •Patients who refused to participate in the survey and who did not sign informed consent
- •Patients with ASA IV or more
- •Patients under 60 years
- •Severe psychiatric disorders involving the use of psychopharmaceuticals back three months
- •All patients who have other fractures in addition to hip fractures
- •Polytrauma
- •All patients scheduled for more than one surgical intervention during the procedure, or within the next 8 weeks
- •Patients who have been diagnosed with dementia, and / or are receiving anti-dementia drugs
Outcomes
Primary Outcomes
change in cognition
Time Frame: preoperatively/postoperative follow up 2 months
MoCA scale (Montreal Cognitive Assessment), F-A-S test
change in anxiety and depression
Time Frame: preoperatively/postoperative follow up 2 months
The HAD Scale (The Hospital Anxiety and Depression Scale)
change in quality of life
Time Frame: preoperatively/postoperative follow up 2 months
EQ-5D-5L Questionnaire