Mycophenolate Mofetil (MMF): A Long-Term Data Evaluation

University of California, Los Angeles0 个研究点目标入组 651 人开始时间: 2006年4月最近更新: 2010年7月13日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: University of California, Los Angeles
入组人数: 651

研究概览研究设计入排标准研究者记录与标识符相似试验

研究概览

简要总结

The purposes of this study are:

To review past clinical use of mycophenolate mofetil (MMF) in kidney transplant patients;
To discover why doses were modified and how those modifications affected the survival and health of the transplanted kidney; and
To determine whether, therefore, the side effects of MMF that result in dose alterations are related to outcome.

详细描述

Objectives:

We propose collecting data on the MMF total daily dose and regimens used in our transplant population from 1995 to 2003. We will assess why doses were modified and how those modifications affected graft survival, and whether, therefore, the side effects of MMF that result in dose alterations are related to outcome.

Implementation

Phase I - To describe initial MMF dosing and subsequent changes
Phase II - To explore the potential effect of the above on graft outcomes
Phase III - To explore reasons for dose changes and how these relate to tolerability

PHASE I

研究设计

研究类型: Observational
时间视角: Retrospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Renal transplant recipients of either a cadaveric or living donor kidney.
•18 years of age or older.

排除标准

•Multiple organ transplant recipients.
•Prior kidney transplant recipients.

研究者

发起方

University of California, Los Angeles

申办方类型

Other

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