COVID-19 Seroconversion Among Medical and Paramedical Staff in Emergency, ICU and Infectious Disease Services During the 2020 Epidemic
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,177
- 试验地点
- 2
- 主要终点
- Quantify the proportion of patients with documented Sars-CoV2 infection among medical and paramedical staff
研究概览
简要总结
The epidemic due to the Sars-CoV2 virus is spreading in France, without knowning precisely since when the virus has actually circulated on the territory. Data from China but also systematic samples taken from the passengers of the Diamond Princess boat also report almost 50% of asymptomatic forms of Covid-19. The medical and paramedical staff of the front-line services for the care of patients infected with Covid-19 are in fact potentially exposed to the risk of occupational contamination due to the large number of patients treated, including in the pre-epidemic phase. Therefore, and despite the application of standard protective measures, it is possible that a certain number of these personnel already have or will contract Covid-19 disease, including in its asymptomatic form.
详细描述
The epidemic due to Sars-CoV2 is spreading in France, without it being knowning precisely since when the virus actually circulated on the territory. Data from China but also systematic samples taken from the passengers of the boat Diamond Princess also report almost 50% of asymptomatic forms of Covid-19. Medical and paramedical staff are in fact potentially exposed to the risk of professional contamination, with probably a different risk between the first-line referent hospitals and the others, due to the large number of patients treated in the first, including in the pre-epidemic phase (average of 190 consultants per day at the emergency department Pitié-Salpêtrière for example). Therefore, and despite the application of standard protective measures, it is possible that a certain number of these personnel already have or will contract Covid-19 disease, including in its asymptomatic form. Knowledge of this seroconversion rate, if it is found to be higher than that of the general population, could lead to a review of the measures to protect personnel from other emerging infectious risks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Any permanent medical or paramedic staff of participating services who have given written consent to participate
- •Having a social security insurance.
排除标准
- •Non-permanent staff (occasional staffing), administrative staff, technical staff of participating services.
- •Staff who were not active during the inclusion period.
结局指标
主要结局
Quantify the proportion of patients with documented Sars-CoV2 infection among medical and paramedical staff
时间窗: 3 months
Sars-CoV2 seroconversion is defined by a T0 sample with no specific antibody (negative) and M3 sample with the presence of specific IgG.
次要结局
- Identification of risk factors for seroconversion(3 months)
- " Describe symptomatic infections for personnel developing acute clinical (respiratory or digestive) viral syndrome "(3 months)
- Quantify the proportion of asymptomatic infections among staff who have seroconverted(3 months)