NCT01986374已完成不适用
Intrauterine Injection of Human Chorionic Gonadotropin to Enhance Embryo Implantation
Servy Massey Fertility Insititute1 个研究点 分布在 1 个国家目标入组 75 人开始时间: 2013年6月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- HCG enhances pregnancy rate
研究概览
简要总结
The endometrium is deprived of signals form the embryo in IVF conditions. Studies suggest that placing HCG into the uterus prior to embryo transfer can enhance implantation.
详细描述
The study is in pilot phase, uncontrolled. The risks appear to be minimal and there are conflicting new reports being announced.
A small amount of fluid with HCG is injected into the uterus. HCG is a potent signal to the uterus for preparation for implantation.
This is not a funded study. Three published studies suggest the approach is valid; one refutes the concept.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 47 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •infertility patients undergoing IVF with good expectation of two embryos day 3 or day
- •must speak and read English. Includes donor eggs.
排除标准
- •abnormal uterus
研究组 & 干预措施
HCG is introduced with small catheter.
Experimental
phase 1 non randomized pilot
干预措施: HCG is introduced (Drug)
结局指标
主要结局
HCG enhances pregnancy rate
时间窗: 9 months.
compare pregnancy rates to established clinical norms.
次要结局
- ongoing pregnancy rate(22 months)
- implantation rate(18 months)
研究者
研究点 (1)
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