跳至主要内容
临床试验/NCT01986374
NCT01986374已完成不适用

Intrauterine Injection of Human Chorionic Gonadotropin to Enhance Embryo Implantation

Servy Massey Fertility Insititute1 个研究点 分布在 1 个国家目标入组 75 人开始时间: 2013年6月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
75
试验地点
1
主要终点
HCG enhances pregnancy rate

研究概览

简要总结

The endometrium is deprived of signals form the embryo in IVF conditions. Studies suggest that placing HCG into the uterus prior to embryo transfer can enhance implantation.

详细描述

The study is in pilot phase, uncontrolled. The risks appear to be minimal and there are conflicting new reports being announced.

A small amount of fluid with HCG is injected into the uterus. HCG is a potent signal to the uterus for preparation for implantation.

This is not a funded study. Three published studies suggest the approach is valid; one refutes the concept.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
21 Years 至 47 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • infertility patients undergoing IVF with good expectation of two embryos day 3 or day
  • must speak and read English. Includes donor eggs.

排除标准

  • abnormal uterus

研究组 & 干预措施

HCG is introduced with small catheter.

Experimental

phase 1 non randomized pilot

干预措施: HCG is introduced (Drug)

结局指标

主要结局

HCG enhances pregnancy rate

时间窗: 9 months.

compare pregnancy rates to established clinical norms.

次要结局

  • ongoing pregnancy rate(22 months)
  • implantation rate(18 months)

研究者

发起方
Servy Massey Fertility Insititute
申办方类型
Other
责任方
Sponsor

研究点 (1)

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