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Influencing Factors on Gait Variability in PD

Conditions
Parkinson Disease
Registration Number
NCT05109897
Lead Sponsor
National Yang Ming Chiao Tung University
Brief Summary

The principal motor features of Parkinson's disease (PD) include rigidity, tremor, bradykinesia, and postural instability. These motor deficits might cause gait dysfunction including reduced gait velocity, stride length, arm swing, and increased gait variability. Among these, increase in gait variability increased fall risk and served as a marker of disease progression. Previous studies reported that some factors might influence gait variability. However, which one contributes most has not yet been verified. Therefore, the purpose of the present study is to identify the more related influencing factors on gait variability in people with PD.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Idiopathic PD
  • Hoehn and Yahr stages I through III
  • Ability to stand and walk 5 m independently with or without any walking aids
  • Stable medication usage
Exclusion Criteria
  • Unstable medical conditions
  • Any neurological, cardiopulmonary or orthopedic problem/diseases that may interfere with participating the study

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Walking speed10 minutes

Using GAITRite system to evaluate

Sensory organization test20 minutes

Using NeuroCom Smart Balance Master to measure

Part III of the Unified Parkinson's Disease Rating Scale20 minutes

The score ranged from 0 to 72. Higher scores show increased severity.

Montreal Cognitive Assessment20 minutes

The score ranged from 0 to 30. Higher scores show better cognitive function.

Gait variability10 minutes

Using GAITRite system to measure coefficient of variation

Tinetti Balance Scale10 minutes

The score ranged from 0 to 28. Higher scores show better balance.

New freezing of gait questionnaire15 minutes

The score ranged from 0 to 29. Higher scores show increased severity in freezing of gait.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University

🇨🇳

Taipei, Taiwan

Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University
🇨🇳Taipei, Taiwan

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