Influencing Factors and Improving Strategy on Gait Variability in People With Parkinson's Disease
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Walking speed
研究概览
简要总结
The principal motor features of Parkinson's disease (PD) include rigidity, tremor, bradykinesia, and postural instability. These motor deficits might cause gait dysfunction including reduced gait velocity, stride length, arm swing, and increased gait variability. Among these, increase in gait variability increased fall risk and served as a marker of disease progression. Previous studies reported that some factors might influence gait variability. However, which one contributes most has not yet been verified. Therefore, the purpose of the present study is to identify the more related influencing factors on gait variability in people with PD.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 40 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Idiopathic PD
- •Hoehn and Yahr stages I through III
- •Ability to stand and walk 5 m independently with or without any walking aids
- •Stable medication usage
排除标准
- •Unstable medical conditions
- •Any neurological, cardiopulmonary or orthopedic problem/diseases that may interfere with participating the study
结局指标
主要结局
Walking speed
时间窗: 10 minutes
Using GAITRite system to evaluate
Sensory organization test
时间窗: 20 minutes
Using NeuroCom Smart Balance Master to measure
Part III of the Unified Parkinson's Disease Rating Scale
时间窗: 20 minutes
The score ranged from 0 to 72. Higher scores show increased severity.
Montreal Cognitive Assessment
时间窗: 20 minutes
The score ranged from 0 to 30. Higher scores show better cognitive function.
Gait variability
时间窗: 10 minutes
Using GAITRite system to measure coefficient of variation
Tinetti Balance Scale
时间窗: 10 minutes
The score ranged from 0 to 28. Higher scores show better balance.
New freezing of gait questionnaire
时间窗: 15 minutes
The score ranged from 0 to 29. Higher scores show increased severity in freezing of gait.
次要结局
未报告次要终点
研究者
Yea-Ru Yang
Professor
National Yang Ming Chiao Tung University