Influencing Factors and Improving Strategy on Gait Variability in People With Parkinson's Disease
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Parkinson Disease
- Sponsor
- National Yang Ming Chiao Tung University
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Walking speed
- Last Updated
- 4 years ago
Overview
Brief Summary
The principal motor features of Parkinson's disease (PD) include rigidity, tremor, bradykinesia, and postural instability. These motor deficits might cause gait dysfunction including reduced gait velocity, stride length, arm swing, and increased gait variability. Among these, increase in gait variability increased fall risk and served as a marker of disease progression. Previous studies reported that some factors might influence gait variability. However, which one contributes most has not yet been verified. Therefore, the purpose of the present study is to identify the more related influencing factors on gait variability in people with PD.
Investigators
Yea-Ru Yang
Professor
National Yang Ming Chiao Tung University
Eligibility Criteria
Inclusion Criteria
- •Idiopathic PD
- •Hoehn and Yahr stages I through III
- •Ability to stand and walk 5 m independently with or without any walking aids
- •Stable medication usage
Exclusion Criteria
- •Unstable medical conditions
- •Any neurological, cardiopulmonary or orthopedic problem/diseases that may interfere with participating the study
Outcomes
Primary Outcomes
Walking speed
Time Frame: 10 minutes
Using GAITRite system to evaluate
Sensory organization test
Time Frame: 20 minutes
Using NeuroCom Smart Balance Master to measure
Part III of the Unified Parkinson's Disease Rating Scale
Time Frame: 20 minutes
The score ranged from 0 to 72. Higher scores show increased severity.
Montreal Cognitive Assessment
Time Frame: 20 minutes
The score ranged from 0 to 30. Higher scores show better cognitive function.
Gait variability
Time Frame: 10 minutes
Using GAITRite system to measure coefficient of variation
Tinetti Balance Scale
Time Frame: 10 minutes
The score ranged from 0 to 28. Higher scores show better balance.
New freezing of gait questionnaire
Time Frame: 15 minutes
The score ranged from 0 to 29. Higher scores show increased severity in freezing of gait.