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Clinical Trials/NCT05027555
NCT05027555
Unknown
Not Applicable

Effect of Multisensory Training on Gait Variability in People With Parkinson's Disease

National Yang Ming Chiao Tung University0 sites40 target enrollmentSeptember 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Parkinson Disease
Sponsor
National Yang Ming Chiao Tung University
Enrollment
40
Primary Endpoint
Gait variability
Last Updated
4 years ago

Overview

Brief Summary

People with Parkinson's disease (PD) were characterized by many motor symptoms, including rigidity, postural instability, bradykinesia, and resting tremor. These motor symptoms might cause gait dysfunction. Gait dysfunction represented a common sign of PD, including reduced gait velocity, reduced stride length, reduced arm swing, and increased gait variability. Poor postural control in people with PD might result to increase gait variability and then increase fall risk. Previous studies reported that proprioceptive-vestibular multisensory training improved postural stability in people with PD. However, no literature investigated the effects of proprioceptive-vestibular multisensory training on gait variability. Therefore, the purpose of this study is to examine the effect of proprioceptive-vestibular multisensory training on gait variability in people with PD.

Registry
clinicaltrials.gov
Start Date
September 1, 2021
End Date
December 31, 2022
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Yea-Ru Yang

Professor

National Yang Ming Chiao Tung University

Eligibility Criteria

Inclusion Criteria

  • Idiopathic PD
  • Hoehn and Yahr stage I to III
  • Age 60\~80 y/o
  • Mini-Mental State Examination (MMSE) ≥24
  • Ability to ambulate independently (with or without walking aid)

Exclusion Criteria

  • Affecting the peripheral vestibular system
  • Medical condition that substantially influenced their gait and balance performance
  • People had joined any rehabilitation past 1 month

Outcomes

Primary Outcomes

Gait variability

Time Frame: Change from baseline at 6 weeks

Using GAITRite system to measure coefficient of variation

Secondary Outcomes

  • Sensory organization test(Change from baseline at 6 weeks)
  • Gait performance(Change from baseline at 6 weeks)
  • Timed up and go test(Change from baseline at 6 weeks)
  • Dynamic Gait Index(Change from baseline at 6 weeks)

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