跳至主要内容
临床试验/NCT05027555
NCT05027555Unknown不适用

Effect of Multisensory Training on Gait Variability in People With Parkinson's Disease

National Yang Ming Chiao Tung University0 个研究点目标入组 40 人开始时间: 2021年9月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
40
主要终点
Gait variability

研究概览

简要总结

People with Parkinson's disease (PD) were characterized by many motor symptoms, including rigidity, postural instability, bradykinesia, and resting tremor. These motor symptoms might cause gait dysfunction. Gait dysfunction represented a common sign of PD, including reduced gait velocity, reduced stride length, reduced arm swing, and increased gait variability. Poor postural control in people with PD might result to increase gait variability and then increase fall risk. Previous studies reported that proprioceptive-vestibular multisensory training improved postural stability in people with PD. However, no literature investigated the effects of proprioceptive-vestibular multisensory training on gait variability. Therefore, the purpose of this study is to examine the effect of proprioceptive-vestibular multisensory training on gait variability in people with PD.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
50 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Idiopathic PD
  • Hoehn and Yahr stage I to III
  • Age 60~80 y/o
  • Mini-Mental State Examination (MMSE) ≥24
  • Ability to ambulate independently (with or without walking aid)

排除标准

  • Affecting the peripheral vestibular system
  • Medical condition that substantially influenced their gait and balance performance
  • People had joined any rehabilitation past 1 month

结局指标

主要结局

Gait variability

时间窗: Change from baseline at 6 weeks

Using GAITRite system to measure coefficient of variation

次要结局

  • Sensory organization test(Change from baseline at 6 weeks)
  • Gait performance(Change from baseline at 6 weeks)
  • Timed up and go test(Change from baseline at 6 weeks)
  • Dynamic Gait Index(Change from baseline at 6 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yea-Ru Yang

Professor

National Yang Ming Chiao Tung University

相似试验