跳至主要内容
临床试验/NCT01935024
NCT01935024Unknown不适用

Assessing the Benefits of an Outpatient Aerobic Activity Program in Patients With Alzheimer's Disease

University Health Network, Toronto2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2013年8月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
60
试验地点
2
主要终点
Neuropsychological Test Battery

研究概览

简要总结

Exercise has been shown to be beneficial for the brain. The investigators would like to test this specifically for those diagnosed with Alzheimer's disease. This study will involve 30 randomized patients to take part in the out-patient exercise program and 30 patients to continue with their regular activities over a 6-month period. Once that period is over, half of the 30 patients who participated in the outpatient exercise program will continue in the program and the other half will be randomized to independently continue to exercise. The investigators hypothesize that exercising will benefit the patient by slowing the dementia process, improving behavioral symptoms, and decreasing volume loss of certain brain regions. Each person will perform personalized exercise regimens, MR imaging and neuropsychological tests will be used to measure the benefits of exercise. Ultimately, the hope is that the results of this study could be used to facilitate exercise programs for patients. Enrollment is completely voluntary and all personal data obtained will remain confidential.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
60 Years 至 95 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

研究组 & 干预措施

Normal Activity level

No Intervention

Personalized Exercise Regimen

Active Comparator

干预措施: Personalized Exercise Regimen (Other)

结局指标

主要结局

Neuropsychological Test Battery

时间窗: Throughout first 6 months of patient participation

The test battery selected comprises of standardized, validated tests focusing on domains including: attention \& concentration, executive functioning, learning and memory, visuospatial, language and semantic memory, pre-morbid intellectual functioning, and speed of processing.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Carmela Tartaglia

MD, FRCPC

University Health Network, Toronto

研究点 (2)

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