Skip to main content
Clinical Trials/NCT05177458
NCT05177458
Completed
Not Applicable

The Effects of Acute Aerobic Exercise on Therapeutic Safety Learning

Thomas Adams1 site in 1 country12 target enrollmentApril 14, 2022
ConditionsPTSD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
PTSD
Sponsor
Thomas Adams
Enrollment
12
Locations
1
Primary Endpoint
Change in participant heart rate
Status
Completed
Last Updated
last year

Overview

Brief Summary

The proposed project seeks to demonstrate that a brief bout of aerobic exercise can improve a particular type of therapeutic learning among victimins of interpersonal violence with or without posttraumatic stress disorder (PTSD).

Detailed Description

The proposed study has one aim: Specific Aim: To examine the effects of acute exercise on the consolidation of therapeutic safety learning. It is hypothesized that participants who engage in 30-min of moderate-intensity aerobic exercise following the first session of imaginal exposure will show larger between-session (visit 2 to 3) reductions in heart rate and anxiety during imaginal exposure to trauma narratives compared to participants who engage in light-intensity exercise.

Registry
clinicaltrials.gov
Start Date
April 14, 2022
End Date
July 18, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Thomas Adams
Responsible Party
Sponsor Investigator
Principal Investigator

Thomas Adams

Assistant Professor

University of Kentucky

Eligibility Criteria

Inclusion Criteria

  • Experience of interpersonal violence
  • English speaking
  • Medically healthy

Exclusion Criteria

  • Any endorsed medical concerns related to physical activity (as probed in the phone screening questions regarding cardiovascular, pulmonary, or metabolic disease and as assessed via the Physical Activity Readiness Questionnaire (PAR-Q), which probes into participants' history of heart conditions, chest pain, dizziness, loss of consciousness, bone/joint problems, and medication history). Participants would not be excluded if they report this condition being "controlled" or "addressed" through medication or lifestyle change, such as regular exercise.
  • Major medical disorders (such as cancer, AIDS)
  • Psychotic disorders
  • Intellectual disabilities
  • Developmental disorders
  • Active substance use disorders
  • Pregnancy or probably pregnancy
  • Body mass index greater than or equal to 35
  • Daily cannabis use
  • History of any cardiac disease

Outcomes

Primary Outcomes

Change in participant heart rate

Time Frame: 24 hours (visit 2), 48 hours (visit 3)

Participant heart rate will be measured at baseline and after each imagery trial using a BIOPAC Bionomadix photo plethysmogram.

Change in participant subjective emotional ratings

Time Frame: 24 hours (visit 2), 48 hours (visit 3)

Participant anxiety will be measured at baseline and after each imagery trial.

Change in participant electrodermal response

Time Frame: 24 hours (visit 2), 48 hours (visit 3)

Participant skin conductance activity will be measured at baseline and during each imagery trial using a pair of BIOPAC Bionomadix electrodermal activity electrodes

Study Sites (1)

Loading locations...

Similar Trials