The Effects of Acute Aerobic Exercise on Therapeutic Safety Learning
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Change in participant heart rate
研究概览
简要总结
The proposed project seeks to demonstrate that a brief bout of aerobic exercise can improve a particular type of therapeutic learning among victimins of interpersonal violence with or without posttraumatic stress disorder (PTSD).
详细描述
The proposed study has one aim:
Specific Aim: To examine the effects of acute exercise on the consolidation of therapeutic safety learning. It is hypothesized that participants who engage in 30-min of moderate-intensity aerobic exercise following the first session of imaginal exposure will show larger between-session (visit 2 to 3) reductions in heart rate and anxiety during imaginal exposure to trauma narratives compared to participants who engage in light-intensity exercise.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 21 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Experience of interpersonal violence
- •English speaking
- •Medically healthy
排除标准
- •Any endorsed medical concerns related to physical activity (as probed in the phone screening questions regarding cardiovascular, pulmonary, or metabolic disease and as assessed via the Physical Activity Readiness Questionnaire (PAR-Q), which probes into participants' history of heart conditions, chest pain, dizziness, loss of consciousness, bone/joint problems, and medication history). Participants would not be excluded if they report this condition being "controlled" or "addressed" through medication or lifestyle change, such as regular exercise.
- •Major medical disorders (such as cancer, AIDS)
- •Psychotic disorders
- •Intellectual disabilities
- •Developmental disorders
- •Active substance use disorders
- •Pregnancy or probably pregnancy
- •Body mass index greater than or equal to 35
- •Daily cannabis use
- •History of any cardiac disease
- •Inability to provide informed consent
- •Physical disabilities that prohibit task performance (such as deafness or blindness)
- •Self-reported history of loss of consciousness (greater than 30 minutes)
结局指标
主要结局
Change in participant heart rate
时间窗: 24 hours (visit 2), 48 hours (visit 3)
Participant heart rate will be measured at baseline and after each imagery trial using a BIOPAC Bionomadix photo plethysmogram.
Change in participant subjective emotional ratings
时间窗: 24 hours (visit 2), 48 hours (visit 3)
Participant anxiety will be measured at baseline and after each imagery trial.
Change in participant electrodermal response
时间窗: 24 hours (visit 2), 48 hours (visit 3)
Participant skin conductance activity will be measured at baseline and during each imagery trial using a pair of BIOPAC Bionomadix electrodermal activity electrodes
次要结局
未报告次要终点
研究者
Thomas Adams
Assistant Professor
University of Kentucky