An Exploratory Investigation of a Supplement to Promote Brain Health

Not Applicable

Completed

• Conditions: Cognitive Change; Memory Deficits; Stress
• Interventions: Dietary Supplement: The Daily Supplement

• Registration Number: NCT05520424
• Lead Sponsor: Parable

Brief Summary

Providing a combination of synergistic dietary supplements, such as vitamins B6, B12, and folate, as well as curcumin, lemon balm, and American ginseng is hypothesized to promote brain health and aid with brain fog, mental clarity, ability to handle stress, mood, focus, and productivity, as well as promote overall well-being.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-15
• Study First Submitted: 2022-08-26
• Study First Submitted QC: 2022-08-26
• Study First Posted: 2022-08-29
• Primary Completion: 2022-10-30
• Study Completion: 2022-10-30
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-01
• Last Update Posted: 2024-04-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• In good general health with no major chronic conditions (e.g., diabetes, coronary heart disease, etc.)

Exclusion Criteria

• Females who are pregnant or breastfeeding
• Anyone currently taking other supplements
• Anyone with a known allergic reaction
• Previous head trauma
• Anyone with chronic diseases such as diabetes, coronary heart disease, or cancer.
• Any psychological, mental, or neurodevelopmental disorders
• Consumes nicotine or marijuana in any form
• Previous or current alcohol addiction
• Consume more than 10 drinks per week

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
The Daily Supplement	The Daily Supplement	Participants will use test product daily, and complete Biomarker assessments (at 1st dose, Day 7, Day 31), as well as surveys (at 1st dose, Day 7, Day 31), and Cognitive battery Assessments (at 1st dose, Day 7, Day 31).

Primary Outcome Measures

Name	Time	Method
Perceived changes in mental health symptoms as measured by Questionnaires	31 days	Questionnaires measure perceived changes in mental health symptoms (e.g., anxiety levels, mental clarity) and stress management on a scale of 0 (low levels of mental health symptoms) to 10 (very high levels of mental health symptoms)
Perceived changes in stress management as measured by Questionnaires	31 days	Questionnaires measure perceived changes in stress management on a scale of 0 (poor ability to manage stress) to 10 (excellent ability to manage stress)

Secondary Outcome Measures

Name	Time	Method
Changes in Cognitive Functioning	31 days	Cognitive battery questionnaires measure executive functioning, long term memory, working memory, and attention.

Trial Locations

Locations (1)

Citruslabs; 🇺🇸 Santa Monica, California, United States